Description

2-(2-Cyanophenyl)-3'-Trifluoromethylacetophenone is a high-value, multi-functional organic intermediate characterized by its distinct aromatic ketone structure incorporating both cyano and trifluoromethyl substituents. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry to create specialized ligands for catalytic systems or metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing advanced polymers, liquid crystals, or organic electronic materials due to its conjugated system and functional groups.
• Fluorescent Probe Synthesis: The aromatic and electron-withdrawing groups make it a candidate for constructing molecular probes and sensors.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	2-(2-Cyanophenyl)-3'-Trifluoromethylacetophenone
CAS No.	898784-47-9
Molecular Formula	C16H10F3NO
Molecular Weight	289.26 g/mol
Synonyms	1-[2-(2-Cyanophenyl)-2-oxoethyl]-3-(trifluoromethyl)benzene; 2'-Cyanobenzoyl-3-(trifluoromethyl)acetophenone; 2-(2-Cyanobenzoyl)-3'-trifluoromethylacetophenone; α-(2-Cyanophenyl)-3'-(trifluoromethyl)acetophenone; 3'-Trifluoromethyl-2-(2-cyanophenyl)acetophenone; 2-Cyanophenyl 3-(Trifluoromethyl)phenyl ketone (variation); [2-Cyanophenyl][3-(trifluoromethyl)phenyl]methanone (variation)
EINECS	Contact for details

Quality Control

Our 2-(2-Cyanophenyl)-3'-Trifluoromethylacetophenone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality systems support development under cGMP guidelines for pharmaceutical applications, ensuring traceability and reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.