Description

2-(2-Cyanophenyl)-2'-Trifluoromethylacetophenone is a high-value, multi-functional organic intermediate featuring both cyano and trifluoromethyl groups on a biphenyl ketone scaffold. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers requiring specific fluorinated aromatic units.
• Chemical Biology Probes: Utilized to build fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	2-(2-Cyanophenyl)-2'-Trifluoromethylacetophenone
CAS No.	898784-45-7
Molecular Formula	C₁₆H₁₀F₃NO
Molecular Weight	289.25 g/mol
Synonyms	2'-(Trifluoromethyl)-[1,1'-biphenyl]-2-acetonitrile; 2-(2-Cyanophenyl)-2'-(trifluoromethyl)acetophenone; 2'-Trifluoromethyl-2-cyanobiphenyl; [1,1'-Biphenyl]-2-acetonitrile, 2'-(trifluoromethyl)-; α-Oxo-2'-(trifluoromethyl)[1,1'-biphenyl]-2-acetonitrile; 2-Cyano-2'-(trifluoromethyl)benzophenone; (2-Cyanophenyl)(2-(trifluoromethyl)phenyl)methanone
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Cyanophenyl)-2'-Trifluoromethylacetophenone is produced under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.