Description

2-(4-Cyanophenyl)-2'-Iodoacetophenone is a high-purity, specialized organic intermediate featuring both cyano and iodo functional groups on a diaryl ketone scaffold. This unique bifunctional structure makes it a valuable building block for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or requiring halogenated aromatic systems.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the iodo and cyano groups contribute to biological activity and molecular diversity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands for transition metal catalysis or organocatalysts.
• Material Science Precursor: Employed in the research of organic electronic materials, such as OLEDs or conductive polymers, due to its electron-withdrawing cyano group and potential for cross-coupling reactions via the iodo substituent.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological processes, leveraging the reactivity of the iodine atom for bioconjugation.

Basic Information

Product Name	2-(4-Cyanophenyl)-2'-Iodoacetophenone
CAS No.	898784-41-3
Molecular Formula	C15H10INO
Molecular Weight	347.15 g/mol
Synonyms	2'-Iodo-2-(4-cyanophenyl)acetophenone; 1-(4-Cyanophenyl)-2-(2-iodophenyl)ethan-1-one; 2-(4-Cyanophenyl)-2'-(iodo)acetophenone; α-(2-Iodophenyl)-4-cyanobenzyl ketone; 4-Cyano-α-(2-iodobenzyl)acetophenone; (4-Cyanophenyl)(2-iodophenyl)methanone (tautomeric form); 898784-41-3
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Cyanophenyl)-2'-Iodoacetophenone is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from advanced techniques like HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.