Description

2-(3-Cyanophenyl)-4'-Iodoacetophenone is a high-purity, specialized organic building block featuring both cyano and iodo functional groups on a biaryl ketone scaffold. This unique structure makes it a valuable intermediate for advanced synthesis in pharmaceutical research and material science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its reactive halogen and nitrile sites.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution, enabling rapid diversification of chemical space.
• Life Science Reagents: Used in the preparation of biochemical probes, fluorescent tags, and molecular imaging agents for diagnostic applications.

Basic Information

Product Name	2-(3-Cyanophenyl)-4'-Iodoacetophenone
CAS No.	898784-39-9
Molecular Formula	C15H10INO
Molecular Weight	347.15 g/mol
Synonyms	4'-Iodo-2-(3-cyanophenyl)acetophenone; 1-[4-(Iodophenyl)]-2-(3-cyanophenyl)ethanone; 2-(3-Cyanophenyl)-1-(4-iodophenyl)ethan-1-one; 3-Cyano-α-(4-iodobenzyl)acetophenone; 898784-39-9; 4-Iodophenyl 3-cyanobenzyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Cyanophenyl)-4'-Iodoacetophenone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.