Description

2-(3-Cyanophenyl)-3'-Iodoacetophenone is a high-purity, specialized organic intermediate featuring both cyano and iodo functional groups on a phenylacetophenone scaffold. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in cross-coupling reactions and as a precursor for functionalized ligands.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated or nitrile-containing motifs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides where its halogen atom facilitates further functionalization.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems due to its reactive handles.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	2-(3-Cyanophenyl)-3'-Iodoacetophenone
CAS No.	898784-37-7
Molecular Formula	C15H10INO
Molecular Weight	347.15 g/mol
Synonyms	3'-Iodo-2-(3-cyanophenyl)acetophenone; 1-[3-(3-Cyanophenyl)phenyl]-2-iodoethanone; 2-Iodo-1-[3'-(3-cyanophenyl)phenyl]ethanone; 3-Cyano-3'-iodobenzophenone; (3-Cyanophenyl)(3-iodophenyl)methanone; 898784-37-7; AI3-52395
EINECS	Contact for details

Quality Control

Our 2-(3-Cyanophenyl)-3'-Iodoacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.