Description

2-(4-Bromophenyl)-4'-Trifluoromethylacetophenone CAS NO 898784-27-5 is a high-purity, advanced pharmaceutical intermediate characterized by its bromophenyl and trifluoromethyl functional groups. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Material Science: Used in the research and development of specialty polymers and liquid crystals, where its aromatic and halogenated structure can modify material properties.
• Organic Synthesis: An important reagent for cross-coupling reactions (e.g., Suzuki, Stille) and other transformations in complex molecule construction for academic and industrial research.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on molecular reactivity and physicochemical properties.

Basic Information

Product Name	2-(4-Bromophenyl)-4'-Trifluoromethylacetophenone
CAS No.	898784-27-5
Molecular Formula	C15H10BrF3O
Molecular Weight	343.14 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-2-(4-bromophenyl)ethanone; 2-(4-Bromophenyl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one; 4'-Trifluoromethyl-2-(4-bromophenyl)acetophenone; 4-Bromo-α-(4-trifluoromethylbenzoyl)benzyl; (4-Bromophenyl)[4-(trifluoromethyl)phenyl]methanone (tautomeric form); p-Bromophenyl p-Trifluoromethylphenyl Ketone
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-4'-Trifluoromethylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.