Description

2-(4-Chlorophenyl)-4'-Iodoacetophenone is a specialized halogenated acetophenone derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which facilitates the introduction of both chlorophenyl and iodoacetophenone moieties into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex intermediates and active ingredients. Its precise reactivity profile makes it an essential reagent for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators, leveraging its halogenated aromatic structure.
• Material Science Chemistry: Acts as a monomer or cross-linking agent in the research and development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	2-(4-Chlorophenyl)-4'-Iodoacetophenone
CAS No.	898784-08-2
Molecular Formula	C14H10ClIO
Molecular Weight	356.59 g/mol
Synonyms	1-[4-(4-Chlorophenyl)-2-oxo-2-phenylethyl]-4-iodobenzene; 4'-Iodo-2-(4-chlorophenyl)acetophenone; 2-(p-Chlorophenyl)-4'-iodoacetophenone; (4-Chlorophenyl)(4-iodophenyl)methanone, α-methyl-; 4-Chlorophenyl 4-iodobenzyl ketone; 898784-08-2; p-Chlorophenyl p-iodobenzyl ketone
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-4'-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our commitment to quality assurance guarantees material consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.