Description

2-(3-Chlorophenyl)-3'-Iodoacetophenone CAS NO 898784-04-8 is a specialized halogenated acetophenone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and iodo substituents on aromatic rings, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators where the halogenated aromatic system is essential for bioactivity.
• Material Science: Building block for creating specialized polymers, liquid crystals, or organic electronic materials due to its rigid, substituted aromatic core.
• Chemical Synthesis: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Heck) for introducing complex aryl groups.
• Academic & R&D: Essential reagent in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	2-(3-Chlorophenyl)-3'-Iodoacetophenone
CAS No.	898784-04-8
Molecular Formula	C14H10ClIO
Molecular Weight	356.59 g/mol
Synonyms	1-(3-Chlorophenyl)-2-(3-iodophenyl)ethanone; 3'-Iodo-2-(3-chlorophenyl)acetophenone; 2-(3-Chlorophenyl)-1-(3-iodophenyl)ethanone; 3-Chloro-3'-iodobenzophenone (common misnomer); α-(3-Chlorophenyl)-3-iodoacetophenone; (3-Chlorophenyl)(3-iodophenyl)methanone (tautomeric form); 898784-04-8; 3-Iodophenyl 3-chlorophenyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chlorophenyl)-3'-Iodoacetophenone is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the exacting standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.