Description

2-(2-Chlorophenyl)-2'-Iodoacetophenone CAS NO 898784-00-4 is a specialized halogenated acetophenone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chlorine and iodine substituents on aromatic rings, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) and other transition metal-catalyzed transformations due to its reactive halogen atoms.
• Agrochemical Research: Intermediate in the development of novel pesticides and herbicides, leveraging its halogenated aromatic structure.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers and advanced organic materials.
• Academic & R&D: Serves as a reagent in university and industrial research laboratories for methodological studies and novel compound library generation.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2-(2-Chlorophenyl)-2'-Iodoacetophenone
CAS No.	898784-00-4
Molecular Formula	C14H10ClIO
Molecular Weight	356.59 g/mol
Synonyms	2'-Iodo-2-(2-chlorophenyl)acetophenone; 1-(2-Chlorophenyl)-2-(2-iodophenyl)ethan-1-one; α-(2-Chlorophenyl)-2-iodoacetophenone; 2-Chloro-2'-iodobenzyl Phenyl Ketone; (2-Chlorophenyl)(2-iodophenyl)methanone (tautomeric form); Halogenated Acetophenone Derivative; CAS 898784-00-4
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Chlorophenyl)-2'-Iodoacetophenone is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard quality commitment includes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements under cGMP or ISO 9001 guidelines as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.