Description

2-(4-Bromophenyl)-4'-Iodoacetophenone is a high-purity, diaryl ketone derivative featuring both bromine and iodine substituents, making it a versatile and valuable synthetic intermediate. This compound is critical for facilitating advanced cross-coupling reactions and serving as a key precursor in complex organic synthesis. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly in medicinal chemistry research for oncology and CNS diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Acts as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-(4-Bromophenyl)-4'-Iodoacetophenone
CAS No.	898783-98-7
Molecular Formula	C14H10BrIO
Molecular Weight	401.04 g/mol
Synonyms	1-[4-(4-Bromophenyl)-2-oxoethyl]-4-iodobenzene; 4'-Iodo-2-(4-bromophenyl)acetophenone; 2-(4-Bromophenyl)-1-(4-iodophenyl)ethanone; (4-Bromophenyl)(4-iodophenyl)methanone, methylene derivative; p-Bromophenyl p-iodophenyl ketone, methylene derivative; 898783-98-7; BRII Ketone Intermediate
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-4'-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under ISO and cGMP aligned standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.