Description

2-(4-Bromophenyl)-3'-Iodoacetophenone is a high-purity, bifunctional aromatic ketone building block of significant interest in advanced organic synthesis. Its distinct molecular architecture, featuring both bromo and iodo substituents, makes it a versatile precursor for constructing complex molecular frameworks via selective cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for structure-activity relationship (SAR) studies.
• Material Science Precursor: Acts as a building block for the synthesis of organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Cross-Coupling Reactions: An essential substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions due to its reactive bromo and iodo functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Item	Detail
Product Name	2-(4-Bromophenyl)-3'-Iodoacetophenone
CAS No.	898783-96-5
Molecular Formula	C14H10BrIO
Molecular Weight	401.04 g/mol
Synonyms	3'-Iodo-2-(4-bromophenyl)acetophenone; 1-[3-Iodophenyl]-2-(4-bromophenyl)ethanone; 2-(4-Bromophenyl)-1-(3-iodophenyl)ethan-1-one; (3'-Iodophenyl)(4-bromophenyl)methanone (tautomeric form); 4-Bromo-α-(3-iodobenzoyl)toluene; Bifunctional Aromatic Ketone Building Block; Halogenated Acetophenone Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-3'-Iodoacetophenone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard research-grade material is characterized by techniques including HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.