Description

2-(4-Bromophenyl)-2'-Iodoacetophenone is a high-purity, bifunctional aromatic ketone building block of significant interest in advanced organic synthesis. Its distinct molecular architecture, featuring both bromo and iodo substituents on separate phenyl rings, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of specialized intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring diaryl ketone or biaryl motifs.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings, leveraging both the bromo and iodo functional groups for sequential or selective functionalization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where its halogenated structure can be incorporated into bioactive molecules.
• Ligand and Catalyst Development: Acts as a starting material for the preparation of specialized ligands for metal catalysis or as a core structure in organic electronic materials.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways in organic chemistry.
• Material Science Precursor: Potential use in the synthesis of monomers or building blocks for polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	2-(4-Bromophenyl)-2'-Iodoacetophenone
CAS No.	898783-94-3
Molecular Formula	C14H10BrIO
Molecular Weight	401.04 g/mol
Synonyms	2'-Iodo-2-(4-bromophenyl)acetophenone; 1-(4-Bromophenyl)-2-(2-iodophenyl)ethan-1-one; 2-(4-Bromophenyl)-2-iodoacetophenone; α-(4-Bromophenyl)-α'-(2-iodophenyl)acetophenone; 4-Bromo-2'-iodoacetophenone (ambiguous, verify structure); (4-Bromophenyl)(2-iodophenyl)methanone precursor.
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-2'-Iodoacetophenone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee consistency and support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents (e.g., DMF, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.