Description

2-(3-Bromophenyl)-4'-Iodoacetophenone is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors or other biologically active scaffolds.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products, leveraging its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of both bromo and iodo functional groups, allowing for selective, sequential functionalization.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic organic chemistry and methodology development.

Basic Information

Product Name	2-(3-Bromophenyl)-4'-Iodoacetophenone
CAS No.	898783-92-1
Molecular Formula	C14H10BrIO
Molecular Weight	401.04 g/mol
Synonyms	1-[4-(Iodophenyl)]-2-(3-bromophenyl)ethanone; 4'-Iodo-2'-(3-bromobenzoyl)acetophenone; 3'-Bromo-4-iodobenzophenone; (3-Bromophenyl)(4-iodophenyl)methanone; 898783-92-1; Ethanone, 2-(3-bromophenyl)-1-(4-iodophenyl)-; 1-(4-Iodophenyl)-2-(3-bromophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)-4'-Iodoacetophenone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to traceability and documentation supports your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.