Description

2-(2-Bromophenyl)-4'-Iodoacetophenone is a high-purity, specialized organic intermediate featuring both bromo and iodo substituents on a phenylacetophenone core structure. This compound is valued for its dual halogen functionality, which provides distinct reactivity sites for sequential cross-coupling and functionalization reactions in advanced synthetic pathways. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the bromo and iodo groups allow for precise structural modifications.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of specialized organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions such as Suzuki, Heck, and Sonogashira couplings due to its reactive halogen atoms.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the creation of new chemical libraries.
• Fine Chemical Synthesis: Utilized in the custom synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-(2-Bromophenyl)-4'-Iodoacetophenone
CAS No.	898783-86-3
Molecular Formula	C14H10BrIO
Molecular Weight	401.04 g/mol
Synonyms	1-(4-Iodophenyl)-2-(2-bromophenyl)ethanone; 2-Bromo-2'-(4-iodobenzoyl)biphenyl; 4'-Iodo-2-(2-bromophenyl)acetophenone; 2-(2-Bromophenyl)-1-(4-iodophenyl)ethan-1-one; (2-Bromophenyl)(4-iodophenyl)methanone (tautomeric form); 898783-86-3; BPIAP
EINECS	Contact for details

Quality Control

Our 2-(2-Bromophenyl)-4'-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.