Description

8-Oxo-8-(4-Trifluoromethylphenyl)Octanenitrile is a high-value, fluorinated organic building block characterized by its ketone and nitrile functional groups. This compound matters for its role as a versatile synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated components in advanced electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, imparting unique properties like chemical resistance or altered surface energy.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating complex biaryl structures common in medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying enzyme mechanisms or protein-ligand interactions.

Basic Information

Product Name	8-Oxo-8-(4-Trifluoromethylphenyl)Octanenitrile
CAS No.	898783-74-9
Molecular Formula	C₁₅H₁₆F₃NO
Molecular Weight	283.29 g/mol
Synonyms	8-Oxo-8-[4-(trifluoromethyl)phenyl]octanenitrile; 4'-Trifluoromethyl-γ-oxobenzenebutanenitrile; 8-(4-Trifluoromethylphenyl)-8-oxooctanenitrile; γ-Oxo-4'-(trifluoromethyl)benzenebutanenitrile; 1-(4-Trifluoromethylphenyl)-1,7-dioxoheptanenitrile; Octanenitrile, 8-oxo-8-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 8-Oxo-8-(4-Trifluoromethylphenyl)Octanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of high-purity material for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.