Description

3',5'-Difluoro-3-(4-Thiomethylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a thiomethylphenyl group, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	3',5'-Difluoro-3-(4-Thiomethylphenyl)Propiophenone
CAS No.	898781-81-2
Molecular Formula	C16H14F2OS
Molecular Weight	292.34 g/mol
Synonyms	1-[3,5-Difluorophenyl]-3-[4-(methylthio)phenyl]-1-propanone; 3,5-Difluoro-3'-(methylthio)propiophenone; 3-(4-Methylsulfanylphenyl)-1-(3,5-difluorophenyl)propan-1-one; 898781-81-2; Propiophenone, 3',5'-difluoro-3-(4-(methylthio)phenyl)-; 3',5'-Difluoro-3-(4-methylmercaptophenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3-(4-Thiomethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.