Description

4'-Chloro-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated and thiomethyl-substituted aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel APIs, especially in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Research & Development: Used in the synthesis of new-generation herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Organic Chemistry Research: A valuable substrate for studying cross-coupling reactions, fluorination effects, and sulfur chemistry in academic and industrial R&D labs.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysts or monomers for advanced polymers.

Basic Information

Product Name	4'-Chloro-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone
CAS No.	898781-65-2
Molecular Formula	C16H14ClFOS
Molecular Weight	308.80 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)-3-[4-(methylthio)phenyl]propan-1-one; 3-(4-Methylthiophenyl)-1-(4-chloro-2-fluorophenyl)propan-1-one; 4'-Chloro-2'-fluoro-3-(4-methylthiophenyl)propiophenone; 898781-65-2; Propiophenone, 4'-chloro-2'-fluoro-3-[4-(methylthio)phenyl]-; 1-(4-Chloro-2-fluorophenyl)-3-(4-methylsulfanylphenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our production of 4'-Chloro-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.