Description

2'-Chloro-4'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone is a high-value, synthetically versatile organic intermediate characterized by its distinct halogenated and sulfur-containing aromatic structure. This compound matters for its critical role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and sulfur motifs for bioactivity.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and liquid crystals with specific electronic or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, and other transformations to introduce complex arylpropylketone functionalities.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling in related API manufacturing.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone
CAS No.	898781-61-8
Molecular Formula	C16H14ClFOS
Molecular Weight	308.80 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-[4-(methylthio)phenyl]propan-1-one; 3-(4-Methylthiophenyl)-1-(2-chloro-4-fluorophenyl)propan-1-one; 2'-Chloro-4'-fluoro-3-(4-methylmercaptophenyl)propiophenone; 2-Chloro-4-fluoro-3'-(4-methylthiophenyl)propiophenone; 898781-61-8; Propiophenone, 2'-chloro-4'-fluoro-3-(4-(methylthio)phenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Chloro-4'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.