Description

4'-Bromo-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated and sulfur-containing aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor in organic synthesis for introducing bromo, fluoro, and thiomethyl functional groups into complex molecules.
• Material Science: Potential intermediate in the research and development of specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for global clients.

Basic Information

Item	Details
Product Name	4'-Bromo-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone
CAS No.	898781-59-4
Molecular Formula	C16H14BrFOS
Molecular Weight	353.25 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-3-[4-(methylthio)phenyl]propan-1-one; 3-(4-Methylthiophenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one; 898781-59-4; 4'-Bromo-2'-fluoro-3-(4-methylthiophenyl)propiophenone; 4'-Bromo-2'-fluoro-3-(4-(methylthio)phenyl)propiophenone; 1-(4-Bromo-2-fluorophenyl)-3-(4-methylsulfanylphenyl)propan-1-one
EINECS	Contact for details

Quality Control

Every batch of 4'-Bromo-2'-Fluoro-3-(4-Thiomethylphenyl)Propiophenone is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or manufacturing protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.