Description

3-(4-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone is a high-value organic intermediate characterized by its unique trifluoromethyl and thiomethyl functional groups. This compound is critical for the synthesis of advanced pharmaceutical agents and agrochemicals, where its structure imparts desirable metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with unique optical and electronic properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	3-(4-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898781-57-2
Molecular Formula	C17H15F3OS
Molecular Weight	324.36 g/mol
Synonyms	1-[3-(4-Methylsulfanylphenyl)propyl]-4-(trifluoromethyl)benzene; 3-(4-Methylthiophenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 4'-Trifluoromethyl-3-(4-thiomethylphenyl)propiophenone; 3-(p-Methylthiophenyl)-4'-(trifluoromethyl)propiophenone; 898781-57-2; Propiophenone, 3-(4-(methylthio)phenyl)-1-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 3-(4-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO 9001 compliant manufacturing processes, ensuring the material meets the exacting standards of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.