Description

3-(4-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone CAS NO 898781-55-0 is a high-value, specialized organic intermediate featuring a unique trifluoromethyl and thiomethylphenyl substitution pattern. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms and sulfur-containing moieties is required to modulate biological activity and physicochemical properties. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research, where the trifluoromethyl group enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity imparted by the sulfur and fluorine functional groups.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated monomer or intermediate in the production of high-performance electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique thermal, optical, or surface properties for high-tech applications.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science exploration in academic and industrial R&D laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	3-(4-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone
CAS No.	898781-55-0
Molecular Formula	C17H13F3OS
Molecular Weight	310.34 g/mol
Synonyms	1-[3-(4-Methylsulfanylphenyl)-3-oxopropyl]-4-(trifluoromethyl)benzene; 3-Oxo-3-[4-(trifluoromethyl)phenyl]-1-(4-methylthiophenyl)propane; 3-(4-Methylthiophenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 3-(p-Methylthiophenyl)-3'-(trifluoromethyl)propiophenone; Propiophenone, 3-(4-(methylthio)phenyl)-3'-(trifluoromethyl)-; 4'-(Trifluoromethyl)-3-(4-methylmercaptophenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3-(4-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring cGMP compliance for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.