Description

3-(3,5-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone CAS NO 898781-19-6 is a high-purity fluorinated aromatic ketone intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring a trifluorinated aromatic ring, makes it a valuable building block for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex, fluorinated molecular architectures for various R&D applications.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Item	Details
Product Name	3-(3,5-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898781-19-6
Molecular Formula	C17H14F3O
Molecular Weight	294.29 g/mol
Synonyms	1-[3,5-Bis(trifluoromethyl)phenyl]-3-(3,5-dimethylphenyl)propan-1-one (IUPAC); 3',4',5'-Trifluoro-3,5-dimethylpropiophenone; 3-(3,5-Dimethylphenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; 898781-19-6; Trifluoromethylated Propiophenone Derivative; Fluorinated Aromatic Ketone Intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-(3,5-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, GC, NMR, and IR spectroscopy. Our quality protocols are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ensure batch-to-batch consistency for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.