Description

3',5'-Difluoro-3-(3,5-Dimethylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise and reliable fluorinated intermediates for research and production, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorinated phenylpropiophenone structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and liquid crystals, leveraging its aromatic and ketone functionalities.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for studying biological systems.

Basic Information

Product Name	3',5'-Difluoro-3-(3,5-Dimethylphenyl)Propiophenone
CAS No.	898781-16-3
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3-(3,5-dimethylphenyl)-1-propanone; 3-(3,5-Dimethylphenyl)-1-(3,5-difluorophenyl)propan-1-one; 3,5-Difluoro-3'-(3,5-dimethylphenyl)propiophenone; 3',5'-Difluoro-3,5-dimethylpropiophenone; Propiophenone, 3',5'-difluoro-3-(3,5-dimethylphenyl)-; 898781-16-3; 3-(3,5-Dimethylphenyl)-1-(3,5-difluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3-(3,5-Dimethylphenyl)Propiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.