Description

3,5-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-value, multifunctional organic intermediate featuring a benzophenone core with a spirocyclic acetal-protected amine side chain. This compound matters for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily needed by pharmaceutical R&D departments, contract research and manufacturing organizations (CROs/CMOs), and advanced fine chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially protein kinase inhibitors.
• Chemical Biology Probe Development: Used to create tagged or modified molecules for studying biological pathways and target engagement.
• Advanced Material Research: Serves as a monomer or functional component in the development of specialty polymers with unique optical or electronic properties.
• Agrochemical Synthesis: Intermediate for creating new-generation crop protection agents with enhanced efficacy.
• Academic & Industrial Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	3,5-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898781-05-0
Molecular Formula	C25H27F2NO3
Molecular Weight	427.49 g/mol
Synonyms	2'-(8-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)methyl)-3,5-difluorobenzophenone; 3,5-Difluoro-2'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone; 8-[(3,5-Difluoro-2-benzoylphenyl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane; Benzophenone, 3,5-difluoro-2'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-
EINECS	Contact for details

Quality Control

Our production of 3,5-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be customized to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.