Description

4'-Chloro-3-(3,5-Dimethylphenyl)-2'-Fluoropropiophenone is a high-value, multi-substituted aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring chloro, fluoro, and dimethylphenyl substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory drugs, and kinase inhibitors.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, substituted aromatic core.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4'-Chloro-3-(3,5-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898780-96-6
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	2'-Fluoro-4'-chloro-3-(3,5-dimethylphenyl)propiophenone; 1-(4-Chloro-2-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one; 3-(3,5-Dimethylphenyl)-1-(2-fluoro-4-chlorophenyl)propan-1-one; 898780-96-6; 4'-Chloro-2'-fluoro-3-(3,5-dimethylphenyl)propiophenone; Propiophenone, 4'-chloro-3-(3,5-dimethylphenyl)-2'-fluoro-
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3-(3,5-Dimethylphenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, and we support custom purity specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.