Description

3-(3,5-Dimethylphenyl)-4'-Trifluoromethylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and dimethylphenyl functional groups. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical R&D departments and fine chemical manufacturers need this reliable building block to develop new therapeutic agents with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for CNS and metabolic disease targets.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial research laboratories for constructing complex molecular architectures via cross-coupling and condensation reactions.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine substitution on molecular reactivity and physicochemical properties.

Basic Information

Product Name	3-(3,5-Dimethylphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898780-88-6
Molecular Formula	C18H17F3O
Molecular Weight	306.33 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-(3,5-dimethylphenyl)propan-1-one; 4'-Trifluoromethyl-3-(3,5-dimethylphenyl)propiophenone; 3,5-Dimethyl-4'-trifluoromethylpropiophenone; Propiophenone, 3-(3,5-dimethylphenyl)-4'-(trifluoromethyl)-; 898780-88-6; 3-(3,5-Dimethylphenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one
EINECS	Contact for details

Quality Control

Our 3-(3,5-Dimethylphenyl)-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; store away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.