Description

3-(3,5-Dimethylphenyl)-2'-Trifluoromethylpropiophenone is a high-purity, specialized organic intermediate featuring a trifluoromethyl group and a dimethylphenyl moiety. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of modern pesticides and herbicides, where the trifluoromethyl group enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the development of advanced electronic display components and organic light-emitting diodes due to its aromatic and fluorinated structure.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling reactions and fluorination chemistry.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-(3,5-Dimethylphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898780-84-2
Molecular Formula	C18H17F3O
Molecular Weight	306.33 g/mol
Synonyms	1-[3-(3,5-Dimethylphenyl)-1-oxopropyl]-2-(trifluoromethyl)benzene; 2'-Trifluoromethyl-3-(3,5-dimethylphenyl)propiophenone; 3,5-Dimethyl-β-phenylpropiophenone, 2'-trifluoromethyl-; Propiophenone, 3-(3,5-dimethylphenyl)-2'-(trifluoromethyl)-; 898780-84-2; 3-(3,5-Dimethylphenyl)-2'-(trifluoromethyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3-(3,5-Dimethylphenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.