Description

3'-Chloro-3-(3,5-Dimethylphenyl)-4'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Organic Ligand Preparation: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: Employed by contract research organizations (CROs) and custom synthesis facilities for client-specific molecule construction.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in cross-coupling and fluorination chemistry.

Basic Information

Product Name	3'-Chloro-3-(3,5-Dimethylphenyl)-4'-Fluoropropiophenone
CAS No.	898780-78-4
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one; 3-(3,5-Dimethylphenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; 3'-Chloro-4'-fluoro-3,5-dimethylpropiophenone; 898780-78-4; Propiophenone, 3'-chloro-3-(3,5-dimethylphenyl)-4'-fluoro-; 3-(3,5-Dimethylphenyl)-1-(3-chloro-4-fluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-3-(3,5-Dimethylphenyl)-4'-Fluoroprophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.