Description

Cyclobutyl 2-(2-Thiomethylphenyl)Ethyl Ketone is a specialized organic building block featuring a cyclobutyl ketone core linked to a thiomethyl-substituted phenyl ring. This unique molecular architecture makes it a valuable intermediate for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, or insecticides, leveraging its sulfur-containing moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors or advanced polymers where the rigid cyclobutyl group can influence material properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function or cellular pathways.

Basic Information

Product Name	Cyclobutyl 2-(2-Thiomethylphenyl)Ethyl Ketone
CAS No.	898780-69-3
Molecular Formula	C14H18OS
Molecular Weight	234.36 g/mol
Synonyms	1-(2-((Methylthio)methyl)phenyl)-3-cyclobutylpropan-1-one; 3-Cyclobutyl-1-[2-[(methylthio)methyl]phenyl]propan-1-one; Cyclobutyl 2-(2-(Methylthio)methylphenyl)ethyl ketone; 898780-69-3; Cyclobutyl(2-(2-(methylthio)methyl)phenyl)ethyl ketone
EINECS	Contact for details

Quality Control

Every batch of Cyclobutyl 2-(2-Thiomethylphenyl)Ethyl Ketone is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.