Description

3',5'-Difluoro-3-(2-Thiomethylphenyl)Propiophenone is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine atoms and a thiomethylphenyl group, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for synthesizing specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3',5'-Difluoro-3-(2-Thiomethylphenyl)Propiophenone
CAS No.	898780-61-5
Molecular Formula	C16H14F2OS
Molecular Weight	292.35 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3-[2-(methylthio)phenyl]propan-1-one; 3',5'-Difluoro-3-(2-methylthiophenyl)propiophenone; 3-(2-Methylsulfanylphenyl)-1-(3,5-difluorophenyl)propan-1-one; 1-(3,5-Difluorophenyl)-3-(2-methylsulfanylphenyl)-1-propanone; 898780-61-5; Propiophenone, 3',5'-difluoro-3-(2-(methylthio)phenyl)-
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3-(2-Thiomethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-quality material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.