Description

3-(2-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone is a high-value, fluorinated organic intermediate characterized by its unique trifluoromethyl and thiomethyl functional groups. This compound is critical for researchers and manufacturers requiring precise molecular architecture for advanced material and pharmaceutical synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Acts as a precursor for advanced electronic materials, contributing to the molecular core of display and lighting technologies.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems used in asymmetric synthesis.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.
• Fluorine Chemistry Studies: Essential for academic and industrial research focused on understanding the influence of fluorine atoms on molecular properties like lipophilicity and metabolic stability.

Basic Information

Product Name	3-(2-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898780-28-4
Molecular Formula	C17H15F3OS
Molecular Weight	324.36 g/mol
Synonyms	1-[3-(2-Methylthiophenyl)-3-oxopropyl]-4-(trifluoromethyl)benzene; 3-Oxo-3-(2-(methylthio)phenyl)-1-(4-(trifluoromethyl)phenyl)propan-1-one; 3-(2-Methylthiophenyl)-1-(4-trifluoromethylphenyl)propan-1-one; 3-(2-Methylmercaptophenyl)-4'-trifluoromethylpropiophenone; 898780-28-4; Propiophenone, 3-(2-(methylthio)phenyl)-1-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 3-(2-Thiomethylphenyl)-4'-Trifluoromethylpropiophenone adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems are designed to support cGMP compliance for pharmaceutical applications and meet the exacting standards of global industrial and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.