Description

3-(2-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone is a specialized organic building block featuring a unique combination of a thiomethylphenyl group and a trifluoromethylpropiophenone moiety. This compound is valued for its role as a key intermediate in advanced synthetic chemistry, enabling the development of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and as a scaffold for library synthesis in medicinal chemistry.
• Ligand & Catalyst Development: Utilized in the design of novel organocatalysts or metal-chelating ligands for asymmetric synthesis.

Basic Information

Product Name	3-(2-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone
CAS No.	898780-25-1
Molecular Formula	C18H15F3OS
Molecular Weight	336.37 g/mol
Synonyms	1-[3-(2-Methylthiophenyl)-3-oxopropyl]-4-(trifluoromethyl)benzene; 3-(2-Methylthiophenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 3-Oxo-3-(4-(trifluoromethyl)phenyl)-1-(2-(methylthio)phenyl)propane; 3-(2-(Methylthio)phenyl)-3'-(trifluoromethyl)propiophenone; 898780-25-1; Propiophenone, 3-(2-(methylthio)phenyl)-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(2-Thiomethylphenyl)-3'-Trifluoromethylpropiophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.