Description

3-(2-Thiomethylphenyl)-2'-Trifluoromethylpropiophenone is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl and thiomethyl-substituted aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group contributes to biological activity.
• Material Science Precursor: Serves as a specialty monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for complex organic transformations, including cross-coupling reactions and fluorination chemistry.
• Ligand Synthesis: Useful for creating novel ligands for catalysis in asymmetric synthesis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(2-Thiomethylphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898780-22-8
Molecular Formula	C17H15F3OS
Molecular Weight	324.36 g/mol
Synonyms	2'-Trifluoromethyl-3-(2-(methylthio)phenyl)propiophenone; 1-[3-(2-Methylsulfanylphenyl)-3-oxopropyl]-2-(trifluoromethyl)benzene; 3-(2-Methylthiophenyl)-2'-(trifluoromethyl)propiophenone; 3-Oxo-3-(2-(methylthio)phenyl)-1-(2-(trifluoromethyl)phenyl)propane; Propiophenone, 3-(2-(methylthio)phenyl)-2'-(trifluoromethyl)-; CAS 898780-22-8
EINECS	Contact for details

Quality Control

Our 3-(2-Thiomethylphenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.