Description

2'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and a thiomethylphenyl moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or intermediate in the synthesis of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating fluorinated probes and tags used in biochemical and medicinal chemistry research.
• Custom Synthesis & Scale-up: Supplied for contract research organizations (CROs) and chemical development companies for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone
CAS No.	898780-19-3
Molecular Formula	C16H15FOS
Molecular Weight	274.35 g/mol
Synonyms	1-(2-Fluorophenyl)-3-[2-(methylthio)phenyl]propan-1-one; 3-(2-(Methylthio)phenyl)-1-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-(2-methylthiophenyl)propiophenone; 2'-Fluoro-3-(2-(methylmercapto)phenyl)propiophenone; 898780-19-3; Propiophenone, 2'-fluoro-3-(2-(methylthio)phenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone is produced and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.