Description

2-(2,3-Difluorobenzoyl)Pyridine is a high-value fluorinated aromatic building block with the CAS number 898780-15-9. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its difluorobenzoyl-pyridine scaffold imparts desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the fluorine atoms for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	2-(2,3-Difluorobenzoyl)Pyridine
CAS No.	898780-15-9
Molecular Formula	C12H7F2NO
Molecular Weight	219.19 g/mol
Synonyms	2-(2,3-Difluorobenzoyl)pyridine; Pyridine, 2-(2,3-difluorobenzoyl)-; 2-Pyridinyl(2,3-difluorophenyl)methanone; (2,3-Difluorophenyl)(pyridin-2-yl)methanone; 898780-15-9; 2-(2,3-Difluorobenzoyl)pyridine; 2-(2,3-Difluorobenzoyl)pyridine (CAS 898780-15-9)
EINECS	Contact for details

Quality Control

Our 2-(2,3-Difluorobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in cGMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.