Description

3'-Chloro-4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and thiomethyl-substituted aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates and proprietary chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex organic molecules, studying reaction mechanisms, and developing new synthetic methodologies.
• Agrochemical Development: Serves as a precursor in the research and production of advanced pesticides and herbicides, leveraging its halogenated phenylpropiophenone core.
• Material Science: Investigated for the synthesis of specialized polymers and liquid crystals where its specific aromatic and sulfur-containing groups impart desired properties.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone
CAS No.	898780-13-7
Molecular Formula	C16H14ClFOS
Molecular Weight	308.80 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-[2-(methylthio)phenyl]propan-1-one; 3'-Chloro-4'-fluoro-3-(2-methylthiophenyl)propiophenone; 898780-13-7; 3-(2-(Methylthio)phenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; Propiophenone, 3'-chloro-4'-fluoro-3-(2-(methylthio)phenyl)-; 1-(3-Chloro-4-fluorophenyl)-3-(2-methylsulfanylphenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.