Description

3-(3,4-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in its precise molecular architecture, which serves as a critical building block for constructing complex molecules in regulated industries. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl and fluorinated aryl groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices due to its fluorinated aromatic system.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A versatile building block for methodological studies in cross-coupling reactions, carbonyl chemistry, and fluorination techniques.

Basic Information

Product Name	3-(3,4-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898779-91-4
Molecular Formula	C17H15F3O
Molecular Weight	292.30 g/mol
Synonyms	1-[3,4-Bis(trifluoromethyl)phenyl]-3-(3,4-dimethylphenyl)propan-1-one; 3',4',5'-Trifluoro-3,4-dimethylpropiophenone; 3,4-Dimethyl-3',4',5'-trifluoropropiophenone; 3-(3,4-Dimethylphenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; Propiophenone, 3-(3,4-dimethylphenyl)-3',4',5'-trifluoro-; CAS 898779-91-4
EINECS	Contact for details

Quality Control

Our production of 3-(3,4-Dimethylphenyl)-3',4',5'-Trifluoropropiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.