Description

3',4'-Difluoro-3-(3,4-Dimethylphenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical building block for the development of novel, complex molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and manufacturers engaged in creating new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where the introduction of fluorine atoms and specific aryl groups is required to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro and dimethylphenyl groups contribute to enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing advanced organic materials, including liquid crystals, polymers, and organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and tags used in studying biological processes and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3',4'-Difluoro-3-(3,4-Dimethylphenyl)Propiophenone
CAS No.	898779-87-8
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(3,4-dimethylphenyl)propan-1-one; 3-(3,4-Dimethylphenyl)-1-(3,4-difluorophenyl)propan-1-one; 3,4-Dimethyl-3',4'-difluoropropiophenone; 898779-87-8; Propiophenone, 3',4'-difluoro-3-(3,4-dimethylphenyl)-
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(3,4-Dimethylphenyl)Propiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.