Description

2'-Chloro-3-(3,4-Dimethylphenyl)-4'-Fluoropropiophenone is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and dimethylphenyl substituents, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and pesticides due to its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for the development of specialty polymers and liquid crystal materials.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a core component in the synthesis of electron-transport or host materials for OLED devices.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Industrial R&D: A valuable reagent for methodology development in cross-coupling and fluorination chemistry.

Basic Information

Product Name	2'-Chloro-3-(3,4-Dimethylphenyl)-4'-Fluoropropiophenone
CAS No.	898779-69-6
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(2-Chlorophenyl)-3-(3,4-dimethylphenyl)-2-fluoro-1-propanone; 2-Chloro-3',4'-dimethyl-4-fluoropropiophenone; 4-Fluoro-2'-chloro-3-(3,4-dimethylphenyl)propiophenone; Propiophenone, 2'-chloro-3-(3,4-dimethylphenyl)-4'-fluoro-; 898779-69-6; 2'-Chloro-3-(3,4-dimethylphenyl)-4'-fluoropropiophenone
EINECS	Contact for details

Quality Control

Every batch of 2'-Chloro-3-(3,4-Dimethylphenyl)-4'-Fluoropropiophenone is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.