Description

4-Chloro-3'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its molecular architecture, featuring both chloro and fluoro substituents on the aromatic rings, makes it a valuable precursor for developing active pharmaceutical ingredients (APIs) with enhanced metabolic stability and binding affinity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions, catalytic processes, and as a standard for analytical method development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	4-Chloro-3'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone
CAS No.	898779-51-6
Molecular Formula	C₁₆H₁₂ClFO₃
Molecular Weight	306.72 g/mol
Synonyms	4-Chloro-3'-(1,3-dioxolan-2-yl)-3-fluorobenzophenone; 3-Fluoro-4-chloro-3'-(1,3-dioxolan-2-yl)benzophenone; 2-[3-(4-Chlorobenzoyl)-4-fluorophenyl]-1,3-dioxolane; Benzophenone, 4-chloro-3'-(1,3-dioxolan-2-yl)-3-fluoro-; 898779-51-6; 4-Chloro-3-fluoro-3'-(1,3-dioxolan-2-yl)benzophenone
EINECS	Contact for details

Quality Control

Our 4-Chloro-3'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.