Description

4'-Bromo-3-(3,4-Dimethylphenyl)-3'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular architecture is required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new therapeutic agents and specialty compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its halogenated phenyl ketone structure.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Stille) to create more complex biaryl systems.
• Material Science: Potential monomer or precursor for specialty polymers and liquid crystals.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR).
• Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4'-Bromo-3-(3,4-Dimethylphenyl)-3'-Fluoropropiophenone
CAS No.	898779-50-5
Molecular Formula	C17H16BrFO
Molecular Weight	335.21 g/mol
Synonyms	1-(4-Bromophenyl)-3-(3,4-dimethylphenyl)-3-fluoropropan-1-one; 3'-Fluoro-4'-bromo-3,4-dimethylpropiophenone; 3-(3,4-Dimethylphenyl)-3-fluoro-1-(4-bromophenyl)propan-1-one; Propiophenone, 4'-bromo-3-(3,4-dimethylphenyl)-3'-fluoro-; 898779-50-5; 4'-Bromo-3',3,4-trimethylpropiophenone (related); 3-Fluoro-3-(3,4-dimethylphenyl)-1-(4-bromophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-(3,4-Dimethylphenyl)-3'-Fluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.