Description

3-(3,4-Dimethylphenyl)-4'-Fluoropropiophenone is a specialized organic intermediate featuring a fluorinated propiophenone core substituted with a dimethylphenyl group. This molecular architecture makes it a valuable building block for the synthesis of more complex chemical entities, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in fine chemical synthesis. The compound's defined structure offers a precise starting point for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced organic electronic materials due to its rigid, conjugated structure and fluorine substitution.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis, fluorination chemistry, and catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3-(3,4-Dimethylphenyl)-4'-Fluoropropiophenone
CAS No.	898779-29-8
Molecular Formula	C17H17FO
Molecular Weight	256.32 g/mol
Synonyms	4'-Fluoro-3-(3,4-dimethylphenyl)propiophenone; 1-[4-Fluorophenyl]-3-(3,4-dimethylphenyl)-1-propanone; 3-(3,4-Dimethylphenyl)-1-(4-fluorophenyl)propan-1-one; 4-Fluoro-β-(3,4-dimethylbenzyl)propiophenone; Propiophenone, 3-(3,4-dimethylphenyl)-4'-fluoro-; 898779-29-8 (CAS Name)
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dimethylphenyl)-4'-Fluoroprophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC/MS for residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.