Description

Cyclobutyl 2-(3,4,5-Trifluorophenyl)Ethyl Ketone is a high-purity fluorinated ketone building block of significant interest in advanced organic synthesis. This compound is valued for its unique cyclobutyl and trifluoromethylphenyl motifs, which are critical for modulating the physicochemical properties of target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing lipophilic and metabolically stable fluorinated aromatic systems.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials that require specific fluorine-containing aromatic units.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and interactions.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization via the ketone group and the aromatic ring in custom synthesis and route scouting.

Basic Information

Product Name	Cyclobutyl 2-(3,4,5-Trifluorophenyl)Ethyl Ketone
CAS No.	898778-74-0
Molecular Formula	C₁₃H₁₃F₃O
Molecular Weight	242.24 g/mol
Synonyms	1-Cyclobutyl-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-cyclobutyl-1-propanone; Cyclobutyl 3-(3,4,5-trifluorophenyl)propyl ketone; (3,4,5-Trifluorophenyl)ethyl cyclobutyl ketone; Ketone, cyclobutyl 2-(3,4,5-trifluorophenyl)ethyl; 898778-74-0
EINECS	Contact for details

Quality Control

Our production of Cyclobutyl 2-(3,4,5-Trifluorophenyl)Ethyl Ketone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a quality system designed to meet the rigorous standards of our global B2B partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.