Description

2',6'-Dichloro-3-(3,4,5-trifluorophenyl)propiophenone is a high-value fluorinated and chlorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine and chlorine substituents contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic or optical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise halogenated scaffold.

Basic Information

Product Name	2',6'-Dichloro-3-(3,4,5-trifluorophenyl)propiophenone
CAS No.	898778-70-6
Molecular Formula	C15H8Cl2F3O
Molecular Weight	341.12 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(2,6-dichlorophenyl)propan-1-one; 2,6-Dichloro-3',4',5'-trifluoropropiophenone; Propiophenone, 2',6'-dichloro-3-(3,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-3-(3,4,5-trifluorophenyl)propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.