Description

3',4'-Difluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate, critical for its role in advanced organic synthesis. This compound matters because its unique polyfluorinated structure provides exceptional electronic properties and metabolic stability, making it a key building block for sophisticated active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel compounds with enhanced efficacy.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms improve lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and liquid crystals with unique optical and electronic properties.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the research and development of electron-transport or host materials for display and lighting technologies.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorinated probes and tags used in imaging and diagnostic assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	3',4'-Difluoro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-64-8
Molecular Formula	C15H9F5O
Molecular Weight	300.23 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3,4,5-Trifluoro-3'4'-difluoropropiophenone; 3-(3,4,5-Trifluorophenyl)-1-(3,4-difluorophenyl)propan-1-one; Propiophenone, 3',4'-difluoro-3-(3,4,5-trifluorophenyl)-; DFTPP (abbreviation); Polyfluorinated Propiophenone Derivative; Fluorinated Aromatic Ketone Intermediate
EINECS	Contact for details

Quality Control

Every batch of 3',4'-Difluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.