Description

3',5'-Dichloro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value, multi-functional organic intermediate characterized by its unique halogenated aromatic structure. This compound is critical for the synthesis of complex molecules where precise halogen substitution patterns are required for activity and selectivity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and fungicides, leveraging the trifluoromethylphenyl moiety for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the development of specialty polymers and liquid crystals, where its halogenated structure can influence material properties like thermal stability and refractive index.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) as a sophisticated electrophile or as a ligand precursor in catalyst design for asymmetric synthesis.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical laboratories.

Basic Information

Product Name	3',5'-Dichloro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-60-4
Molecular Formula	C15H8Cl2F3O
Molecular Weight	341.13 g/mol
Synonyms	1-(3,5-Dichlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3,5-Dichloro-3'-(3,4,5-trifluorophenyl)propiophenone; 3',5'-Dichloro-3-(3,4,5-trifluorophenyl)-1-propanone; 898778-60-4; Propiophenone, 3',5'-dichloro-3-(3,4,5-trifluorophenyl)-; 3-(3,4,5-Trifluorophenyl)-3',5'-dichloropropiophenone
EINECS	Contact for details

Quality Control

Our production of 3',5'-Dichloro-3-(3,4,5-Trifluorophenyl)Propiophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and compliance for demanding pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.