Description

2'-Chloro-4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its complex, multi-fluorinated structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals with enhanced properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing advanced fluorinated polymers and liquid crystals with unique thermal and optical properties.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological mechanisms and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-42-2
Molecular Formula	C15H7ClF4O
Molecular Weight	314.66 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(2-chloro-4-fluorophenyl)propan-1-one; 2-Chloro-4-fluoro-3'-(3,4,5-trifluorophenyl)propiophenone; 898778-42-2; Propiophenone, 2'-chloro-4'-fluoro-3-(3,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2'-Chloro-4'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.