Description

3'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone building block, distinguished by its unique trifluoromethyl and polyfluorinated phenyl substituents. This compound is critical for introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly in the development of protease inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicide and pesticide molecules, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers and ligands used in catalysis and advanced polymer systems.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and fluorination studies to create complex, value-added chemical entities.
• Ligand and Catalyst Development: Utilized in the design of novel fluorinated ligands for transition metal catalysis.

Basic Information

Product Name	3'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-33-1
Molecular Formula	C16H9F6O
Molecular Weight	322.24 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-3-(3,4,5-trifluorophenyl)propan-1-one; 3,4,5-Trifluoro-3'-(trifluoromethyl)propiophenone; 3-(3,4,5-Trifluorophenyl)-1-[3-(trifluoromethyl)phenyl]propan-1-one; 3'-Trifluoromethyl-3-(3,4,5-trifluorophenyl)propiophenone; 898778-33-1; Propiophenone, 3'-trifluoromethyl-3-(3,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.