Description

2'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value, multi-fluorinated aromatic ketone building block. This compound is critical for its role as a key intermediate in the synthesis of advanced pharmaceutical active ingredients and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce trifluoromethyl and polyfluorinated phenyl groups into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas where fluorination enhances metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic systems.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and ligands for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-30-8
Molecular Formula	C16H9F6O
Molecular Weight	322.24 g/mol
Synonyms	1-[2-(Trifluoromethyl)phenyl]-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; 2'-(Trifluoromethyl)-3-(3,4,5-trifluorophenyl)propiophenone; 898778-30-8; Propiophenone, 2'-trifluoromethyl-3-(3,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Trifluoromethyl-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.