Description

2'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique trifluoromethylphenyl and fluoropropiophenone structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at research and development laboratories, pharmaceutical manufacturers, and agrochemical companies seeking to incorporate sophisticated fluorine chemistry into their molecules for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atoms improve lipophilicity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and liquid crystals with unique optical and electronic properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on cross-coupling reactions, carbonyl chemistry, and fluorinated compound libraries.
• PET Tracer Development: Potential use as a synthon in the radiochemical synthesis of Positron Emission Tomography (PET) imaging agents for medical diagnostics.

Basic Information

Product Name	2'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone
CAS No.	898778-27-3
Molecular Formula	C15H9F4O
Molecular Weight	272.23 g/mol
Synonyms	1-(2-Fluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one; 3-(3,4,5-Trifluorophenyl)-1-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-(3,4,5-trifluorophenyl)propiophenone; 898778-27-3; Propiophenone, 2'-fluoro-3-(3,4,5-trifluorophenyl)-; 1-(2-Fluorophenyl)-3-(3,4,5-trifluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluoro-3-(3,4,5-Trifluorophenyl)Propiophenone is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.